Epidemiological study to quantify risks for paediatric computerized tomography and to optimise doses
A large-scale multinational collaborative study has been set up with the objective of providing guidance towards optimisation of doses from paediatric computerized tomography (CT) scans. The specific aims of the EPI-CT study are as follows:
• Describe the pattern of use of CT in different countries and over time;
• Derive individual estimates of organ doses;
• Directly evaluate radiation-related risk of cancer following CT examination; and
• Characterize the quality of CT images in relation to the estimated doses in order to better inform CT imaging practice.
EPI-CT will comprise one of the largest paediatric cohorts for retrospective and prospective follow-up with the aim of detecting potential cases of cancer attributable to exposure and will thereby contribute novel evidence to the existing scientific literature. The main goal is to integrate the cohort studies currently being carried out in Europe (in France and the United Kingdom) and to set up additional studies in eight European countries (Germany, Belgium, Denmark, Spain, Finland, Norway, the Netherlands and Sweden) under the coordination of the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO), jointly with scientists of several countries.